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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Med Sci Sports Exerc. 2015 May;47(5):1095–1103. doi: 10.1249/MSS.0000000000000509

Figure 4. Removing any single 1/wk rest-inserted loading bouts results in a modest osteogenic response to mechanical loading.

Figure 4

Two bouts of rest-inserted loading (d1,8, d1,15, d8,15) were sufficient to demonstrate significant load main effects for p.MAR and p.BFR, but not p.MS (A). There was no significant effect of protocol nor were there any treatment interactions. A comparison of pooled 2, and 3 bouts of loading data compared to 9 bouts of loading demonstrated significant loading and protocol main effects and interaction for p.MAR, p.MS, and p.BFR. Post hoc analysis indicated that 2, 3 and 9 bouts of loading significantly enhanced p.MAR and p.BFR compared to contralateral tibiae, while 3 and 9 bouts of loading were required to significantly enhance p.MS compared to contralateral tibia (*, p<0.05). While 2 bouts of loading generated significantly less p.MAR, p.MS, and p.BFR compared to 3 and 9 bouts of loading (^, p<0.05), no differences were observed between 3 and 9 bouts of loading.