Table 2. Summary of protein responses to CFC and memantine.
| NL | FL | B | RL | B-tm | B-tm-cs | RL vs FL | RL vs NL | |
|---|---|---|---|---|---|---|---|---|
| Hippocampus | ||||||||
| Nuclear | 36+, 3− | 6+, 20− | 41+, 0− | 6+, 20− | 17+, 2− | 50+, 0− | 22+, 0− | 5+, 2− |
| Cytosolic | 23+,14− | 21+,11− | 20+, 3− | 23+, 2− | 7+, 10− | 21+,5− | 3+, 5− | 11+, 4− |
| Membrane | 8+, 6− | 3+, 9− | 6+, 2− | 6+, 7− | 4+, 5− | 9+, 5− | 7+, 0− | 3+, 0− |
| Cortex | ||||||||
| Nuclear | 14+, 13− | 7+,20− | 20+, 5− | 9+, 38− | 14+, 8− | 19+, 0− | 2+,10− | 2+, 13− |
| Cytosolic | 25+, 13− | 6+, 10− | 30+, 12− | 19+, 19− | 15+, 12− | 28+, 3− | 7+, 4− | 10+,4− |
| Membrane | 3+, 12− | 4+, 7− | 6+, 12− | 2+, 20− | 19+, 4− | 16+, 0− | 3+, 6− | 3+, 1− |
Number of proteins that increased (+) and decreased (−) in response to treatment or that differed in Ts65Dn from controls with treatment. Abbreviations as in Table 1.