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. 2015 Mar 20;10(3):e0119034. doi: 10.1371/journal.pone.0119034

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© 2015 Richard et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — The effect of intra-NTS injection of Ex4 on progressive ratio operant responding for sucrose was tested. Ex4 potently decreased the number of sucrose rewards earned (A) and the number of active lever presses (B) in an operant lever-pressing paradigm. Importantly this suppression in food-motivated behavior was not associated with a reduction in locomotor activity (C). n = 11 per each treatment group. ** p<0.01, ***P < 0.0005.