Table 1. Summary of the protective efficacies of the different immunization groups.
Group | No. of mice | Adult worms | Female worms | Eggs in liver | |||
---|---|---|---|---|---|---|---|
No. of worms | Reduction (%) | No. of worms | Reduction (%) | No. of eggs | Reduction (%) | ||
Control | 11 | 28±3 | — | 14±2 | — | 114434±17170 | — |
Ad vector | 12 | 27±3 | 6.47 | 13±2 | 4.88 | 106826±18808 | 6.65 |
rSjTPI | 12 | 21±5 # | 26.67 | 10±2 # | 25.20 | 70993±28772 # | 37.96 |
rAdV-SjTPI.opt | 12 | 14±5 # , * | 50.59 | 6±2 # , * | 54.77 | 54883±26892 # , * | 52.04 |
rAdV-SjTPI.opt + rSjTPI | 12 | 8±2 # , * , & | 72.09 | 4±1 # , * , & | 72.73 | 31891±17776 # , * , & | 72.13 |
# Statistically significant (P<0.01), compared with the control or vector control group.
* Statistically significant (P<0.01), compared with the rSjTPI group.
& Statistically significant (P<0.01), compared with the rSjTPI or rAdV-SjTPI.opt group.