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. 2015 Mar 20;10(3):e0119592. doi: 10.1371/journal.pone.0119592

Table 1. Single-marker analysis of OCD association with catechol-O-methyltransferase and monoamine oxidase A single-nucleotide polymorphisms.

Gene SNP OR CHISQ P CHISQ_PAR P_PAR CHISQ_COM P_COM
COMT rs737866 0.756 6.127 0.013 2.286 0.131 7.86 0.005
rs933271 1.238 3.191 0.074 0.222 0.637 3.413 0.065
rs5993883 1.164 2.042 0.153 1.882 0.17 3.133 0.077
rs740603 0.97 0.091 0.762 2.574 0.109 0.057 0.812
rs4680 1.034 0.099 0.752 1 0.317 0.002 0.96
rs4646316 0.851 1.766 0.184 0.143 0.706 1.325 0.25
rs165774 0.988 0.012 0.911 0.037 0.847 0.026 0.872
rs9332377 0.88 0.832 0.362 0.6 0.439 1.174 0.278
MAO-A rs1465107 0.957 0.066 0.798 0.4 0.527 0.277 0.599
rs1465108 1.016 0.008 0.929 0.026 0.873 0 1
rs6323 1.014 0.007 0.934 1.4 0.237 0.2 0.655
rs979606 1.094 0.269 0.604 0.471 0.493 0.024 0.877
rs979605 1.103 0.343 0.558 0.641 0.423 0.022 0.882

SNP: single-nucleotide polymorphism; TDT: transmission/disequilibrium test; OR: TDT odds ratio; CHISQ: TDT chi-square value; P: TDT p value; CHISQ_PAR: parental discordance test chi-square value; P_PAR: parental discordance test p value; CHISQ_COM: combined test chi-square value; P_COM: combined test p value; COMT: catechol-O-methyltransferase; MAO-A: monoamine oxidase-A