Table 2. Analysis of OCD association with catechol-O-methyltransferase and monoamine oxidase A single-nucleotide polymorphisms in female proband trios.

Gene	SNP	OR	CHISQ	P	CHISQ_PAR	P_PAR	CHISQ_COM	P_COM
COMT	rs737866	0.649	5.541	0.019	0.4	0.527	5.939	0.015
	rs933271	1.137	0.449	0.503	0.667	0.414	0.217	0.641
	rs5993883	1.463	4.699	0.03	2.579	0.108	6.737	0.009
	rs740603	1.295	2.314	0.128	4.167	0.041	4.78	0.029
	rs4680	1.293	2.173	0.14	0.4	0.527	1.573	0.21
	rs4646316	0.893	0.34	0.56	0	1	0.3	0.585
	rs165774	0.875	0.533	0.465	1	0.317	0.194	0.66
	rs9332377	0.783	1.22	0.269	0.111	0.739	0.89	0.345
MAO-A	rs1465107	1.083	0.08	0.777	0.067	0.796	0.015	0.901
	rs1465108	1.087	0.083	0.773	0.067	0.796	0.016	0.9
	rs6323	1.24	0.643	0.423	0.692	0.405	0.13	0.718
	rs979606	1.2	0.455	0.5	0.692	0.405	0.059	0.808
	rs979605	1.269	0.83	0.362	0.692	0.405	0.222	0.637

SNP: single-nucleotide polymorphism; TDT: transmission/disequilibrium test; OR: TDT odds ratio; CHISQ: TDT chi-square value; P: TDT p value; CHISQ_PAR: parental discordance test chi-square value; P_PAR: parental discordance test p value; CHISQ_COM: combined test chi-square value; P_COM: combined test p value; COMT: catechol-O-methyltransferase; MAO-A: monoamine oxidase-A