Table 3. Analysis of OCD association with catechol-O-methyltransferase and monoamine oxidase A single-nucleotide polymorphisms in male proband trios.

Gene	SNP	OR	CHISQ	P	CHISQ_PAR	P_PAR	CHISQ_COM	P_COM
COMT	rs737866	0.827	1.705	0.192	0.889	0.346	2.327	0.127
	rs933271	1.28	2.579	0.108	0.111	0.739	2.689	0.101
	rs5993883	1.037	0.073	0.786	0.067	0.796	0.107	0.743
	rs740603	0.851	1.613	0.204	0.043	0.835	1.332	0.248
	rs4680	0.955	0.114	0.736	1	0.317	0.345	0.557
	rs4646316	1.099	0.424	0.515	0.889	0.346	0.12	0.73
	rs165774	0.918	0.214	0.644	2.667	0.102	0.658	0.417
	rs9332377	0.954	0.048	0.827	0	1	0.037	0.847
MAO-A	rs1465107	1.054	0.053	0.818	0.037	0.847	0.087	0.768
	rs1465108	0.954	0.046	0.829	0.222	0.637	0.154	0.695
	rs6323	1.111	0.21	0.646	0.048	0.827	0.094	0.761
	rs979606	1.077	0.111	0.739	0	1	0.087	0.768
	rs979605	0.827	1.705	0.192	0.889	0.346	2.33	0.127

SNP: single-nucleotide polymorphism; TDT: transmission/disequilibrium test; OR: TDT odds ratio; CHISQ: TDT chi-square value; P: TDT p value; CHISQ_PAR: parental discordance test chi-square value; P_PAR: parental discordance test p value; CHISQ_COM: combined test chi-square value; P_COM: combined test p value; COMT: catechol-O-methyltransferase; MAO-A: monoamine oxidase-A