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. 2015 Mar 20;10(3):e0120700. doi: 10.1371/journal.pone.0120700

Fig 3. Effect of CO on the expression of NLRP3, ASC, and caspase-1 in mesenteric lymph nodes (A) and in ileum mucosa (B) of endotoxin-injected mice.

Fig 3

Mice received by gavage 6.5 mg/kg CO (endotoxin-COL), 13 mg/kg CO (endotoxin-COM), 26 mg/kg CO (endotoxin-COH), or the vehicle (endotoxin-V) every other day 8 times followed by injection with endotoxin from S. typhimurium (i.p., 10 mg/kg body weight). Control mice were pretreated with vehicle (control-V) followed by injection with saline. Samples were collected at 12 h after injection. Data are means ± SDs for three mice in each group. #Significantly different from the control (p < 0.05). a, b, and c not sharing the same letter are significantly different (p < 0.05).