Table 2. Inflammatory markers and biochemical characteristics of type 2 diabetic elderly patients.
All subjects | depressive syndrome | depressive syndrome and MCI | MCI | Controls | Difference (p<0.001) | |
---|---|---|---|---|---|---|
Nr of patients | 276 | 57 | 25 | 62 | 132 | |
CRP (mg/L) | 5.08±2.8 | 5.52±2.5 | 9.77±3.3 | 6.72±1.7 | 3.24±1.3 | a, b, c, d, e, f |
IL-6 (pg/ml) | 4.68±2.5 | 5.22±1.7 | 8.39±1.9 | 6.87±1.2 | 2.71±1.2 | a, b, c, e, f |
TNF-α (pg/ml) | 5.33±2.6 | 5.51±2.1 | 9.02±2.4 | 7.3±1.8 | 3.63±1.5 | a, b, c, d, e, f |
HbA1c (%) | 7.24±0.68 | 7.06±0.6 | 8.02 ± 0.68 | 7.62±0.69 | 7±0.5 | a, b, e, f |
CHOL (mmol/L) | 10.3±2.18 | 11.96±2.12 | 10.75± 2.1 | 10.13±2.2 | 9.58±1.76 | b, c, e |
LDL (mmol/L) | 6.06±1.67 | 7.1±1.8 | 6.54 ± 1.89 | 5.79±1.49 | 5.64±1.5 | b, c, e |
TG (mmol/L) | 9.65±2.23 | 9.16±1.98 | 11.33±2.63 | 10.29±2.66 | 9.24±1.79 | a, b, e, f |
HDL (mmol/L) | 2.5± 0.51 | 2.69±0.37 | 2.15 ± 0.45 | 2.36±0.64 | 2.66±0.44 | a, b, e, f |
a- comparing: depressive syndrome—MCI and depressive syndrome;
b- comparing: depressive syndrome—MCI
c- comparing: depressive syndrome—controls
d- comparing: MCI and depressive syndrome—MCI
e- comparing: MCI and depressive syndrome-controls
f- comparing: MCI—controls
DM2—diabetes type 2, OAD- oral anti-diabetic drug, CVD—cardiovascular disease, HA- hypertension, BMI—body mass index, MoCA—Montreal Cognitive Assessment, GDS—Geriatric Depression Scale
The ANOVA test followed by post-hoc test was used to test for significant differences