Table 1. Demographics.
| ENROLLED | |||
|---|---|---|---|
| HIV+/FIL+ | HIV+/FIL- | Two-sided p-value | |
| Number | 28 | 52^ | NA |
| Gender | |||
| N (%) female | 12 (43%) | 23 (44%) | 1.00 (Fisher’s exact) |
| Language | |||
| N (%) Tamil | 19 (68%) | 38 (73%) | 0.33 (Fisher’s exact) |
| N (%) Telegu | 9 (32%) | 11 (21%) | |
| N (%) other/N/A | 0 (0%) | 3 (6%) | |
| Age | |||
| GM (SD) | 34.0 (6.9) | 34.8 (6.6) | 0.5 (WMW) |
| N (%) on ART | 16 (57%) | 28 (54%)* | 1.00 (Fisher’s exact)* |
| Baseline Labs GM (95% CI) | |||
| Hematology | |||
| Hgb | 12.7 (11.8, 13.5) | 13.1 (12.7, 13.4) | 0.39 (WMW) |
| WBC | 6.4 (5.5, 7.4) | 6.2 (5.7, 6.8) | 0.76 (WMW) |
| % EOS | 6.0 (4.3, 8.3) | 4.8 (3.9, 5.9) | 0.23 (WMW) |
| Plts | 274 (220, 342) | 227 (208, 284) | 0.18 (WMW) |
| Liver function | |||
| ALT | 25 (21, 29) | 26 (22, 30) | 0.99 (WMW) |
| AST | 26 (22, 29) | 28 (24, 31) | 0.66 (WMW) |
| HIV monitoring | |||
| CD4 Count | 370 (281, 488) | 443 (381, 515) | 0.33 (WMW) |
| VL (log 10) | 3.76 (3.32, 4.21) | 3.68 (3.37, 3.99)^ | 0.86 (WMW) |
| Filaria antigen | |||
| Circulating Ag | 1123 (590, 2138) $ | 1.7 (1, 2.6) $ | <0.0001 (WMW) |
Abbreviations: HIV: Human Immunodeficiency Virus; FIL: Filaria (W. bancrofti antigen) positive; GM: geometric mean; SD: standard deviation; WMW: Wilcoxon-Mann-Whitney; ART: highly active antiretroviral therapy, N/A: Not available; %: percent. Hgb: Hemoglobin (gm/dL); WBC: White blood cell count (x 103/mm3); EOS: eosinophils; Plts: platelet count (x103/uL); ALT: alanine transaminase (SGPT, IU/L); AST: aspartate transaminase (SGOT, IU/L); VL: viral load; Ag: antigen.
^ 52 subjects were enrolled, but 1 subject did not have baseline HIV viral load value done. These statistics are on all 52 except for the viral load.
* In addition to the 28 subjects who got ART throughout, there were 2 (3.8%) subjects who got ART only part of the time during the study. Fisher’s exact test excluded those 2 subjects.
$ Measured on only n = 12 in the HIV+/FIL+ group and n = 39 in the HIV+/FIL- group.