Table 4. Results of univariate and multivariate Cox regression analyses in 138 patients.
| Parameter | Unfavorable vs. favorable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age (years) | <60 vs. ≥60 | 1.003 | 0.643–1.565 | 0.989 | |||
| Gender | Female vs. male | 1.293 | 0.622–2.688 | 0.492 | |||
| Smoking | Never vs. Ever | 1.152 | 0.680–1.952 | 0.599 | |||
| Alcohol | Never vs. Ever | 1.153 | 0.656–2.025 | 0.621 | |||
| Node metastasis | N0-N1 vs. N2-N3 | 1.914 | 1.219–3.006 | 0.005* | 1.617 | 1.018–2.567 | 0.042* |
| T stage | T1-T2 vs. T3-T4 | 1.979 | 1.243–3.150 | 0.004* | 1.665 | 1.035–2.679 | 0.035* |
| Differentiation | Poor vs. well and moderate | 1.688 | 1.073–2.656 | 0.023* | 1.532 | 0.963–2.436 | 0.072 |
| Clinical stage | I-II vs. III-IV | 1.949 | 1.013–3.748 | 0.046* | 0.784 | 0.340–1.805 | 0.567 |
| PHLPP1 expression | Low vs. high | 0.353 | 0.167–0.746 | 0.006* | 0.402 | 0.189–0.854 | 0.018* |
| PHLPP2 expression | Low vs. high | 0.385 | 0.184–0.808 | 0.012* | 0.737 | 0.312–1.742 | 0.487 |
HR, hazard ratio; CI, confidence interval.
*P<0.05