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. 2015 Mar 20;10(3):e0119526. doi: 10.1371/journal.pone.0119526

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© 2015 Burke et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — Type 1/Type 2 ratio of CD56^bright NK cells (A), CD56^dim NK cells (B), NKT cells (C) and T cells (D). The data are expressed as percentage following lognormal transformation (A) and percentage (B-D) of cells expressing IL18R1 /IL1RL1. (A) Type 1/Type 2 ratio of CD56^bright NK cells was significantly lower in 2^nd trimester compared with 1^st and 3^rd trimesters in control pregnancies (*P<0.05), but not in T1DM patients. (B) CD56^dim NK cells had significantly higher Type 1/Type 2 ratios in 1^st trimester control than postpartum samples (*P<0.05). CD56^dim NK cells Type 1/Type 2 ratio from T1DM patients did not significantly differ across pregnancy and postpartum. (C) Type 1/Type 2 ratios of NKT cells did not differ significantly across pregnancy and postpartum in control and T1DM patients, or between control and T1DM patients. (D) Type 1/Type 2 ratio for T cells was higher in 1^st than 2^nd trimesters in control pregnancies (*P<0.05), but not in T1DM patients.