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. 2015 Mar 20;10(3):e0119526. doi: 10.1371/journal.pone.0119526

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© 2015 Burke et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — In (A) the percentage of Type 2 CD56^bright NK cells expressing ITGA4 in control patients was significantly increased in the 2^nd trimester versus 1^st and 3^rd trimesters (*P<0.05). No significant differences were detected in T1DM patients. In (B) Log of and (C-D) percentage of Type 2 CD56^bright NK cells expressing SELL (B), CXCR3 (C) and CXCR4 (D) are shown. A significant increase in Type 2 CD56^bright NK cells expressing SELL (B), CXCR3 (C) and CXCR4 (D) was detected in 2^nd compared to 1^st trimester (*P<0.05; **P<0.01). Type 2 CD56^bright NK cells expressing CXCR3 were also significantly higher in 2^nd trimester than postpartum (*P<0.05). Control patients had more Type 2 CD56^bright NK cells expressing SELL (B), CXCR3 (C) and CXCR4 (D) than T1DM patients in 2^nd trimester (#P<0.05).