Table 2. Mean intra-compartment genetic diversity of the six compartments sequenced, namely Infant blood, Mothers plasma, BM-RNA and BM-DNA, as calculated in MEGA Version 6.06.
CASE No. | Mean intra-compartment genetic distance | |||||
---|---|---|---|---|---|---|
INFANT-DBS (n = 11) | MOTHER’S PLA-RNA (n = 11) | LBM-DNA (n = 10) | LBM-RNA (n = 10) | RBM-DNA (n = 10) | RBM-RNA (n = 10) | |
1 | 0.035 | 0.061 | 0.022 | 0.039 | 0.000 | 0.081 |
3 | 0.035 | 0.019 | 0.018 | 0.022 | 0.020 | 0.050 |
4 | 0.013 | 0.035 | 0.032 | 0.002 | 0.039 | 0.001 |
10 | 0.002 | 0.050 | 0.020 | 0.021 | 0.026 | 0.014 |
11 | 0.005 | 0.005 | ND | 0.004 | ND | 0.003 |
12 | 0.004 | 0.012 | 0.026 | 0.001 | 0.016 | ND |
14 | 0.001 | 0.024 | 0.026 | 0.011 | 0.012 | 0.014 |
15 | 0.003 | 0.016 | 0.044 | 0.046 | 0.028 | 0.051 |
18 | 0.001 | 0.014 | 0.001 | ND | 0.001 | 0.014 |
19 | 0.001 | 0.000 | 0.003 | 0.018 | 0.009 | 0.011 |
21 | 0.040 | 0.055 | 0.043 | 0.036 | 0.016 | 0.027 |
Mean diversity ± SD (Range) | 0.013±0.016 (0.001–0.040) | 0.026±0.021 (0.000–0.061) | 0.024±0.014 (0.010–0.044) | 0.020±0.016 (0.001–0.046) | 0.017±0.021 (0.000–0.039) | 0.027±0.026 (0.001–0.081) |
Key: ND = not determined as clones from these compartments could not be generated, LBM-DNA = left breast milk DNA, LBM-RNA = left breast milk RNA, RBM-DNA = right breast milk DNA, RBM-RNA = right breast milk RNA, 1 = T-test p = 0.01, 2 = T-test p = 0.04.