Table 4. Specific Ingenuity biofunctions of transcripts with higher and lower expression between HR and LR PBMC samples at day 28.
Biofunction | mRNA abundance | p-value | Number of involved genes |
---|---|---|---|
adhesion of blood cells | HR > LR; day 28 | 1.30E-04 | 15 |
adhesion of granulocytes | HR > LR; day 28 | 5.77E-03 | 5 |
attachment of cells | HR > LR; day 28 | 3.82E-04 | 7 |
binding of blood cells | HR > LR; day 28 | 2.77E-03 | 9 |
binding of blood platelets | HR > LR; day 28 | 1.88E-05 | 6 |
binding of cells | HR > LR; day 28 | 1.14E-05 | 19 |
cell movement | HR > LR; day 28 | 8.93E-08 | 55 |
cell movement of leukocytes | HR > LR; day 28 | 2.31E-03 | 21 |
cell movement of mononuclear leukocytes | HR > LR; day 28 | 4.01E-03 | 14 |
cell movement of myeloid cells | HR > LR; day 28 | 5.40E-03 | 15 |
cell movement of neutrophils | HR > LR; day 28 | 1.18E-02 | 9 |
cell viability of blood cells | HR > LR; day 28 | 1.09E-02 | 9 |
cell viability of hematopoietic progenitor cells | HR > LR; day 28 | 2.79E-03 | 5 |
chemotaxis of cells | HR > LR; day 28 | 2.51E-04 | 17 |
chemotaxis of leukocytes | HR > LR; day 28 | 2.61E-03 | 12 |
chemotaxis of myeloid cells | HR > LR; day 28 | 1.16E-02 | 9 |
engulfment of cells | HR > LR; day 28 | 1.20E-03 | 12 |
homing of cells | HR > LR; day 28 | 1.85E-04 | 18 |
homing of leukocytes | HR > LR; day 28 | 1.49E-03 | 13 |
invasion of cells | HR > LR; day 28 | 3.49E-04 | 20 |
leukocyte migration | HR > LR; day 28 | 2.22E-04 | 26 |
MAPKKK cascade | HR > LR; day 28 | 1.75E-03 | 8 |
microtubule dynamics | HR > LR; day 28 | 4.47E-06 | 27 |
migration of cells | HR > LR; day 28 | 4.19E-07 | 50 |
morphology of cells | HR < LR; day 28 | 8.06E-04 | 35 |
organization of cytoskeleton | HR > LR; day 28 | 4.26E-07 | 34 |
Metadata of involved genes are displayed in S4 Table. HR—High resisting; LR—Low resisting.