Table 3. Cortex areas with altered cortical surface areas in patients with major depressive disorder, compared to healthy controls.
| Region | Side | Cluster size | MNI coordinates (Maximum vertex) | t Value | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| MDD>HC | ||||||
| Isthmus cingulate | R | 1473 | 16 | −48 | −1 | 3.80 |
| Superior frontal | R | 958 | 15 | −4 | 72 | 2.94 |
| Inferior parietal | L | 799 | −50 | −59 | 44 | 3.17 |
| HC> MDD | ||||||
| Transverse temporal | L | 754 | −40 | −24 | 1 | −2.47 |
| Inferior parietal | R | 359 | 38 | −48 | 40 | −2.47 |
MDD: major depressive disorder. HC: healthy control. L: left; R: right. MNI: Montreal Neurological Institute. P < 0.05 FDR corrected, Cluster size > 200 vertices.