Table 1. Effects of ovariectomy, estrogen and iCR therapy on body weight, lacrimal gland and submandibular gland weight.

	SHAM	OVX	OVX+E	OVX+iCR
N	5	5	5	5
BW initial(g)	251.80±6.22	258.60±6.58	254.80±17.21	265.20±5.26
BW final(g)	278.60±9.63 d g	346.40±30.63 b e	297.00±32.45 d g	340.40±19.14 b e
WGR(%)	10.67±3.96 d g	34.03±12.63 b e	16.65±10.65 d	28.32±5.97 b
UW(mg)	400.08±13.76 d g	88.82±4.35 b e	400.24±9.98 d g	86.44±2.32 b e
LGW(mg)	124.37±11.67 c	158.84±0.019 a	145.16±17.55	139.58±25.94
LGW/BW final (mg/g)	0.45±0.053	0.46±0.07	0.49±0.032	0.47±0.05
SW(mg)	269.28±27.05	288.06±40.43	288.30±26.06	300.66±18.87
SW/BW final (mg/g)	0.96±0.10	0.83±0.13 f	0.98±0.13	1.02±0.09 c

BW, body weight; WGR, weight gain rate; UW, uterus weight; LGW, lacrimal gland weight; LGW/BW final, lacrimal gland and final body weight ratio; SW, submandibular gland weight; SW/BW final, submandibular gland and final body weight ratio. Data are expressed as mean± SEM.

a means p<0.05 vs. SHAM;

b means p<0.01 vs. SHAM;

c means p<0.05 vs. OVX;

d means p<0.01 vs. OVX;

e means p<0.01 vs. OVX+E;

f means p<0.05 vs. OVX+ iCR;

g means p<0.01 vs. OVX+ iCR.