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. 2015 Mar 20;10(3):e0119304. doi: 10.1371/journal.pone.0119304

Fig 4. Loss of Mir223 is associated with an increased stress granulopoiesis response.

Fig 4

(A) Wild-type and Mir223 deficient mice (223KO) were treated with 150 mg/kg of 5-FU and neutrophil counts were followed for 35 days (n = 8–10 mice per cohort from two independent experiments). (B) Representative plots showing Ki-67 and DAPI staining of GMPs. Harvested on day 14 following 5-FU. (C) Shown is the percentage of GMPs in the G2/M/S phase of the cell cycle. All data represent the mean ± SEM. *p<0.05, **p<0.005, ***p<0.001.