Fig 3. Two-dimensional (2D) partial least squares discriminant analysis separation using peptide count concentration-based proteomic measurements in the urine exosome of the rats infected with Leptospira vs control rats without Leptospira infection (n = 3).

Although clear separation between control and infected rat urine exosomes is seen, a fraction of overlap between the infected male and infected female rat urine exosome proteins is observed.