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. 2015 Jan 8;18(2):pyu037. doi: 10.1093/ijnp/pyu037

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© The Author 2015. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Mean differences (SD) in proinflammatory biomarkers between first episode of psychosis (FEP) and controls (univariate analysis). (a) Nuclear transcription factor κB (NFκB) activity in peripheral blood mononuclear cell (PBMC) nuclear extracts from FEP patients (n = 85) and controls (n = 35). (b) Western-blot analysis of isoform 2 of cyclooxygenase (COX2) protein (patients n = 85, controls, n = 88); (c) Inducible nitric oxide synthase (iNOS) in PBMC cytosolic extracts from FEP patients (n = 85) and controls (n = 88); and (d) PGE₂ (patients, n = 85; controls, n = 104). (e) Plasma levels of nitrites (NO⁻ ₂) (patients, n = 85; controls, n = 61). (f) Thiobarbituric acid reactive substances (TBARS) (patients, n = 85; controls, n = 104). AU, arbitrary units. Two-tailed nonparametric Mann-Whitney U test was used. ° represents an atypical value and * an extreme value.