Table 1.
Magnesium sulfate (N= 621) |
Placebo (N= 638) |
P valueb | |
---|---|---|---|
Gestational age at randomization (weeks) | 28.5 ± 2.3 | 28.3 ± 2.3 | 0.10 |
Time from rupture of membranes to randomization (hours) Median [Interquartile range] |
25.3 [11.3, 57.0] | 24.9 [11.7, 56.9] | 0.92 |
Maternal age (years) | 26.8 ± 6.4 | 26.1 ± 6.2 | 0.06 |
Maternal prepregnancy body mass index‡ | 26.3 ± 6.7 | 26.6 ± 6.8 | 0.32 |
Race Black White Hispanic Other |
275 (44.3%) 238 (38.3%) 92 (14.8%) 16 (2.6%) |
286 (44.8%) 238 (36.3%) 98 (15.4%) 16 (2.5%) |
0.98 |
Married (no/total number) (%) | 324/620 (52.3%) | 283/636 (44.5 %) | 0.006 |
Educational level (years) | 11.9 ± 2.4 | 11.9 ± 2.4 | 0.77 |
Nulliparous (%) | 195/621 (31.4%) | 213/638 (33.4%) | 0.45 |
Smoking during pregnancy (%) | 186/621 (30.0%) | 182/638 (28.5%) | 0.58 |
Prior preterm delivery | 183/621 (29.5%) | 187/638 (29.3%) | 0.95 |
Antenatal corticosteroid administration | 602/621 (96.9%) | 622/638 (97.5%) | 0.55 |
IQR interquartile range; SD standard deviation
Data presented as n (%) based on 1259 women at enrollment
χ2, Fisher’s exact, or Wilcoxon rank sum test.
The body mass index is the weight in kilograms divided by the square of the height in meters. Values were available for 558 mothers in the magnesium sulfate group and 578 in the placebo group.