Table 2. Baseline Demographic and Clinical Characteristics of Enrolled Patients.
| Characteristic | Stable (n=100) | Exacerbation (n=85) | |
|---|---|---|---|
|
| |||
| mean (sd) range | mean (sd) range | p-value | |
|
| |||
| BMI | 31.10 (8.5) 18-65 | 32.10 (11.1) 16-79 | n.s. |
| Smoking Pack Year History | 46.48 (27.3) 10-156 | 48.99 (34.5) 10-180 | n.s. |
|
| |||
| % (n) | % (n) | p-value | |
|
| |||
| Percent Predicted FEV1 | |||
|
| |||
| >= 80 | 5(4) | 3(2) | n.s. |
| 50-79 | 42(35) | 39(27) | n.s. |
| 30-49 | 39(33) | 33(23) | n.s. |
| < 30 | 14(12) | 25(17) | n.s. |
|
| |||
| 6 Minute Walk | |||
|
| |||
| >300 m | 55(46) | 43(17) | n.s. |
|
| |||
| Literacy | |||
|
| |||
| Adequate | 93 (91) | 88 (59) | n.s. |
|
| |||
| Age Category | |||
|
| |||
| 40-49 years | 2(2) | 9(8) | <0.01 |
| 50-59 years | 28(28) | 44(37) | |
| 60-69 years | 37(37) | 29(25) | |
| 70+ years | 33(33) | 18(15) | |
|
| |||
| Gender | |||
|
| |||
| Female | 43(43) | 51(43) | n.s. |
|
| |||
| Race | |||
|
| |||
| White | 75(75) | 73(60) | n.s. |
|
| |||
| Comorbidities | |||
|
| |||
| Hypertension | 60(56) | 62(50) | n.s. |
| Angina | 13(12) | 30(24) | <0.01 |
| CAD | 21(20) | 25(20) | n.s. |
| CHF | 18(17) | 19(15) | n.s. |
| MI | 20(19) | 21(17) | n.s. |
| Liver diagnosis | 10(9) | 8(6) | n.s. |
| Kidney diagnosis | 3(3) | 3(2) | n.s. |
| Asthma | 29(27) | 44(35) | 0.03 |
| Diabetes | 34(32) | 31(25) | n.s. |
| Depression | 37(35) | 44(35) | n.s. |
| Anxiety | 33(31) | 48(38) | 0.05 |
| Sleep Disorder | 30(28) | 44(36) | 0.04 |
| Cancer | 24(23) | 26(21) | n.s. |
|
| |||
| Length of COPD Diagnosis | |||
|
| |||
| <1 yr | 4(4) | 17(14) | 0.03 |
| 1-3 yrs | 23(23) | 24(20) | |
| 3-5 yrs | 15(15) | 17(14) | |
| >5 yrs | 57(56) | 43(36) | |
|
| |||
| Exacerbations last 12 Months | |||
|
| |||
| 0 | 68(67) | 7(6) | <0.01 |
| 1 | 17(17) | 28(24) | |
| 2 to 5 | 13(13) | 54(46) | |
| ≥6 | 2(2) | 11(9) | |
|
| |||
| COPD Hospitalizations last 12 Months | |||
|
| |||
| 0 | 87(84) | 15(13) | <0.01 |
| 1 | 9(9) | 46(39) | |
| 2 to 5 | 4(4) | 36(30) | |
| ≥6 | 0(0) | 2(2) | |
|
| |||
| COPD ER Visits last 12 Months | |||
|
| |||
| 0 | 83(81) | 41(35) | <0.01 |
| 1 | 9(9) | 27(23) | |
| 2 to 5 | 7(7) | 29(25) | |
| ≥6 | 1(1) | 2(2) | |
|
| |||
| Current COPD Symptoms | |||
|
| |||
| SOB worsening | 19(19) | 80(68) | <0.01 |
| Cough worsening | 15(15) | 61(52) | <0.01 |
| Increase sputum/mucous | 20(20) | 61(51) | <0.01 |
| Fever | 1(1) | 29(25) | <0.01 |
| Faster Breathing | 11(11) | 66(56) | <.001 |
| Wheezing | 20(20) | 78(65) | <.001 |
| Other | 8(8) | 31(26) | <0.01 |
|
| |||
| COPD Medications | |||
|
| |||
| Antibiotics | 1(1) | 24(20) | <0.01 |
| Beta agonists | 96(94) | 96(80) | n.s. |
| Inhaled steroids | 60(59) | 63(52) | n.s. |
| Systemic steroids | 3(3) | 48(40) | <0.01 |
| Anticholinergenics | 74(72) | 77(64) | n.s. |
n.s.=not significant; NA=not applicable