| TARGETS | |
|---|---|
| Enzymesa | GPCRsb |
| AMPK | Angiotensin AT1 receptor |
| Caspase-3 | β1-adrenoceptor |
| DPP-4, dipeptidyl peptidase-4 | β3-adrenoceptor |
| eNOS | Ion channelsc |
| iNOS | ATP-sensitive K+ channels, Kir6.x |
| nNOS | RyR, ryanodine receptors |
| PDE1 | Transportersd |
| PDE2 | GLUT 4, glucose transporter (SLC2A4) |
| PDE5 | Nuclear hormone receptorse |
| PKG | PPARα |
| ROCK, Rho kinase | PPARβ/δ |
| SERCA | PPARγ |
| sGC, soluble guanylate cyclase | |
| Xanthine oxidase/dehydrogenase |
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