Figure 3.
Involvement of hsp90 in T-induced H2S biosynthesis, evaluated in rat isolated aortic rings incubated with the hsp90 inhibitor GA (20 μM, 15 min) or its vehicle (A). Statistical analysis was by two-way anova with a Bonferroni post hoc test (***P < 0.001 vs. vehicle; n = 6). H2S was determined in aortic tissues treated with T in the presence of GA (20 μM, 15 min) (B). Statistical analysis was by one-way anova with Dunnett's post hoc test [##P < 0.01 vs. basal; °°P < 0.01 vs. L-cysteine (L-Cys); **P < 0.01 vs. L-Cys + T; n = 6].