Table 2.
List of host genes selectively targeted by HIV-1 in vivo. Genes are indicated by gene symbol (numbers of integrants)
| Ikeda_2007a | Maldarelli_2014b | Wagner_2014c | Imamichi_2014d |
|---|---|---|---|
| BACH2 (44) | BACH2 (25) | BACH2 (16) | BACH2 (4) |
| MKL2 (4) | MKL2 (122) | MKL2 (4) | SMC5 (17) |
| STAT5B (16) | STAT5B (18) | SATA5B (4) | |
| SMG1 (9) | CYTH1 (7) | XAF1 (13) | |
| RARRES3 (3) | RPTOR (7) | ARHGP35 (7) | |
| ZGPAT (2) | TAOK1 (8) | CREBBP (3) | |
| EIF4G (3) | TNRC6B (7) | MOB1A (2) | |
| SP192 (2) | PRKCB (7) | MGA (3) | |
| hmRNA (8) | MKL1 (9) | GPC3 (2) | |
| SPTANI (2) | MAP4 (7) | CBL (2) | |
| SPATS2 (4) | PAK2 (10) | PHF (9) | |
| TOP1 (2) | NSD1 (7) | APOBEC3C (15) | |
| DUSP16 (2) | KIAA0319L (12) | MDC1 (57) | |
| SOX5 (4) | NFATC3 (7) | HSF5 (10) | |
| NRF1 (2) | HORMAD2 (64) | RALGPS2 (7) | |
| BTBD9 (6) | OXCT1 (5) | ||
| UBE2H (8) | SMG6 (14) | ||
| TBCD (14) |
Genes associated with cell growth and cell proliferation (italics), genes associated with mitosis (bold italics), genes associated with cancer (bold)
aLongitudinal analysis of IS in seven patients on therapy (>2 years), detected in each gene
bLongitudinal analysis of IS in five well-suppressed patients on cART (>10 years); only genes with >5 integrants are included in the table
cLongitudinal analysis of IS in three well-suppressed patients on cART (>10 years)
dLongitudinal analysis of IS in one patient on therapy (≥15 years)