Figure 1.

PRMT5 is dynamically expressed in the mammalian germline during embryogenesis

1. IF for PRMT5 (green) and OCT4⁺ PGCs (arrows) at E10.5, and MVH⁺ PGCs (arrows) at E11.5 (red).
2. PRMT5 (green) in male gonads at E13.5, E16.5 and P1-2. MVH (red) marks germ cells, with PRMT5 foci (white arrow heads) or MVH foci (red arrow heads).
3. PRMT5 (green) expression in female gonads at E13.5, E16.5 and P1-2. MVH (red) marks germ cells.
4. Summary of expression of PRMT5 in the mammalian germline.

Data information: Two embryos were used in each age. The stainings were performed on wild-type C57BL/6 mice. Scale bar, 20 μm.