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. 2015 Jan 16;34(6):811–827. doi: 10.15252/embj.201489032

Figure 1.

Figure 1

TFG octamers assemble into a cup-like structure in vitro
  1. Montage of class averages and 3D volumes of human TFG (amino acids 1-193; EMDataBank accession code EMD-6076). Two sets of 2D class averages and 3D volumes are shown with the left columns showing the class averages generated by reference-free alignment and classification and the right columns showing 3D RCT volumes corresponding to the class average to the left. Scale bars, 50 Å.
  2. Montage of class averages and 3D volumes of C. elegans TFG (amino acids 1-195; EMDataBank accession code EMD-6075), generated as described in (A). Scale bars, 50 Å.
  3. Superposition of 3D volumes of full-length human TFG and truncated TFG (amino acids 1-193). The truncated form is depicted in yellow, while the full-length form is depicted as gray mesh. The top view (top) exhibits limited differences in the structures, while the side view (bottom) shows extra density in the full-length TFG isoform. Scale bar, 25 Å.