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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Nov 11;1852(1):34–46. doi: 10.1016/j.bbadis.2014.11.006

Figure 7. C66 produced a persistent decrease in the diabetes-induced increase in renal H3K9/14 levels on the promoters of CTGF, PAI-1 and FN-1 genes.

Figure 7

CHIP assay was used to detect the (A, B, C) H3K9/14 levels and (D, E, F) p300 occupancy on the (A) CTGF, (B) PAI-1 and (C) FN-1 promoters at 6 months after treatment (equating to 3 months after treatment termination). Normal mouse IgG was used as a negative control and data were normalized to input DNA samples. n=5; * P < 0.05 vs. control group; # P < 0.05 vs. DM group.