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. 2015 Mar 17;3:e829. doi: 10.7717/peerj.829

Table 4. Top 10 cited primary research miRNA publications.

Rank Citations Title Author Journal Year
1 4,167 Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Lewis BP, et al. Cell 2005
2 3,671 The C-Elegans heterochronic gene Lin-4 encodes small RNAs with antisense complementarity to Lin-14 Lee RC, et al. Cell 1993
3 3,512 MicroRNA expression profiles classify human cancers Lu J, et al. Nature 2005
4 2,337 Mapping and quantifying mammalian transcriptomes by RNA-Seq Mortazavi A, et al. Nature Methods 2008
5 2,291 A microRNA expression signature of human solid tumors defines cancer gene targets Volinia S, et al. PNAS 2006
6 2,168 Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs Lim LP, et al. Nature 2005
7 2,151 Prediction of mammalian microRNA targets Lewis BP et al. Cell 2003
8 2,009 Identification of novel genes coding for small expressed RNAs Lagos-Quintana M et al. Science 2001
9 1,954 Combinatorial microRNA target predictions Krek A et al. Nature Genetics 2005
10 1,851 The nuclear RNase III drosha initiates microRNA processing Lee Y et al. Nature 2003