Figure 3. Example of dinucleotide repeat bias in a human genome.

AT repeats had lower coverage compared to other dinucleotide repeats for human genome NA12878 (Illumina high-coverage paired-end read dataset aligned with BWA to human reference hg18) (DePristo et al., 2011). Dinucleotide repeats less than 20 bases were filtered. Dinucleotide combinations with less than 50 occurrences in the genome are not shown.