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Comparison of TM3C data with existing genome architecture datasets. Eigenvalue decomposition to identify open/closed chromatin compartments of chromosome 17 (a) from the KBM7 cell line assayed by TM3C and (b) from GM06990 cell line assayed by Hi-C [4]. Topological domain calls and contact count heatmaps of a 6 Mb region of chromosome 6 (c) for the KBM7 cell line assayed by TM3C and (d) for the IMR90 cell line assayed by Hi-C [5].
