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. Author manuscript; available in PMC: 2015 Aug 10.
Published in final edited form as: Circulation. 2014 Dec 22;131(6):536–549. doi: 10.1161/CIRCULATIONAHA.114.010696

Table 1.

Cardiovascular Disease Phenotypes Included in Analyses

Cardiovascular Disease Phenotypes
(Named by MeSH Terms)
Cardiovascular Disease Risk Factors
(Named by MeSH Terms)
  • Aortic aneurysm, abdominal

  • Atrial fibrillation

  • Cardiomegaly/cardiomyopathy dilated/heart failure

  • Carotid artery diseases/carotid stenosis

  • Coronary artery disease/ atherosclerosis/ coronary disease/myocardial infarction

  • Death sudden cardiac/arrhythmias cardiac

  • Intracranial aneurysm

  • Stroke

  • Venous thrombosis/venous thromboembolism

  • Cholesterol, LDL/cholesterol/apolipoprotein B

  • Cholesterol, HDL/apolipoprotein A

  • Triglycerides/VLDL-C

  • Lipoprotein (a)

  • Coagulation

  • Diabetes mellitus, type 1

  • Diabetes mellitus, type 2/glucose/insulin

  • Diabetic retinopathy

  • Smoking/tobacco

  • Body mass index/waist-hip ratio/obesity

  • Systolic/diastolic blood pressure/hypertension

  • C-reactive protein/inflammation

HDL indicates high-density lipoprotein; LDL, low-density lipoprotein; MeSH, Medical Subject Headings; VLDL-C, very low-density lipoprotein; and /, similar traits that were merged.