Table 2.
Comparison of pathologic characteristics of ductal carcinoma in situ lesions and treatment modalities between African American and White-American women
| Variable | All Women N= 335 (%) |
African-American N= 100 (%) |
White-American N=235 (%) |
P-Value |
|---|---|---|---|---|
| Histologic Grade | ||||
| 1 | 78(23.7) | 30 (30.9) | 48 (21.4) | .140 |
| 2 | 92 (27.9) | 22 (22.7) | 70 (29.9) | |
| 3 | 158 (47.9) | 45 (46.4) | 113 (48.5) | |
| Missing | 7 | 3 | 4 | |
| Calcification | ||||
| Present | 246 (89.5) | 66 (86.8) | 180 (90.9) | .376 |
| Absent | 28 (10.5) | 10 (13.2) | 18 (9.1) | |
| Missing | 61 | 24 | 37 | |
| Margin | ||||
| Negative | 215 (69) | 64 (69.6) | 151 (68.8) | .918 |
| Negative < 1mm | 68 (22.0) | 20 (21.7) | 48 (22.2) | |
| Positive, focal | 22 (7.0) | 7 (7.6) | 15 (6.8) | |
| Positive, multifocal | 2 (0.6) | 0 | 2 (.9) | |
| Positive, extensive | 4 (1.3) | 1 (1.1) | 3 (1.4) | |
| Missing | 24 | 8 | 16 | |
| Lesion Size in Greatest Dimension in cm (mean± SD) | 1.99 (± 1.9) | 2.13 (± 1.8) | 1.90 (± 1.9) | .362 |
| Necrosis | ||||
| Positive | 83 (30.2) | 27 (32.5) | 56 (29.7) | .590 |
| Negative | 196 (69.8) | 56 (67.5) | 140 (70.7) | |
| Missing | 56 | 17 | 39 | |
| Architectural Pattern | ||||
| Mixed | 122 (46.2) | 35 (44.9) | 87 (46.8) | .440 |
| Solid | 20 (7.6) | 5 (6.4) | 15 (8.1) | |
| Cribriform | 42 (15.9) | 17 (21.8) | 24 (13.4) | |
| Micropapillary | 13 (4.9) | 1 (1.3) | 12 (6.4) | |
| Papillary | 2 (0.8) | 0 | 2 (1.1) | |
| Clinging | 2 (0.8) | 0 | 2 (1.1) | |
| Comedo | 62 (23.1) | 20 (25.6) | 42 (22.6) | |
| Missing | 73 | 22 | 51 | |