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. Author manuscript; available in PMC: 2015 Mar 22.
Published in final edited form as: Breast Cancer Res Treat. 2011 Aug 27;131(2):561–570. doi: 10.1007/s10549-011-1742-5

Table 4.

Adjusted risk for any second breast cancer: multivariate Cox proportional hazard statistics

Variable Women with second
breast cancers
N		 Women without second
breast cancers
N		 HR
(95% CI)1 		P-Value
BCS + Radiation
relative to
Mastectomy		 BCS w/o Rad
relative to
mastect3 		BCS + Radiation
relative to
mastect2 		BCS w/o Rad
relative to
mastect3
Race4
African-American
vs.
White-American
12/2
vs.
6/4
4/2
vs.
6/4
30/32
vs.
87/79
14/32
vs.
42/79		 2.61
(1.27–5.36)		 .01
Margin4
Positive vs. Negative
7 vs. 11
6 vs. 10
20 vs. 53
59 vs. 141
.83
(.46–1.50)		 .53
Presentation5
Mammography
vs.
Palpation		 3 vs. 15

 4 vs. 12

 66 vs. 16

 194 vs. 23

 0.59
(.25–1.40)		 .23
1

Hazard ratio; 95% Confidence Interval;

2

Breast conserving surgery with radiation vs. Mastectomy;

3

Breast conserving surgery without radiation vs. Mastectomy;

4

Adjusted for margin, clinical presentation of cancer, age at the time of diagnosis and body mass index;

4

Adjusted for final treatment, clinical presentation of cancer, age at the time of diagnosis and body mass index

5

Adjusted for final treatment, age, body mass index and margin