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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: J Immunol. 2015 Mar 4;194(7):3035–3044. doi: 10.4049/jimmunol.1402690

Figure 8. TLR stimulation expands cells bearing less negatively charged CDR3 segments.

Figure 8

TLR9 and TLR/IFN stimulation induced less negatively charged CDR3 segments in both non-mutated (A) and mutated (B) sequence subsets relative to mean charges of -0.55 and -0.47 for unstimulated cells. Bars represent mean, error bars represent SEM. † = p < 0.1, * = p < 0.05, ** = p < 0.01. Data represent four independent donors, split across two independent sequencing runs.