Table 2.
Morphological and passive electrical properties of hippocampal principal cells used in the simulations.
| Area | Cell code | Dendritic length (μm) | Dendritic surface (μm2) | Soma surface (μm2) | Input resistance (MΩ) | Membrane resistivity (Ωcm2) |
|---|---|---|---|---|---|---|
| CA1 | 20130613_02 | 10038 | 84706 | 1087 | 71.4 | 47200 |
| 20130613_03 | 6539 | 44687 | 1246 | 78.1 | 22500 | |
| 20130617_02 | 9035 | 53584 | 1084 | 90.0 | 39050 | |
| 20130701_02 | 10763 | 67055 | 593 | 52.3 | 24000 | |
| 20131126_01 | 7675 | 66535 | 462 | 101.9 | 60700 | |
| CA3 | 20131106_02 | 8650 | 49925 | 1046 | 142.3 | 70900 |
| 20131107_01 | 9191 | 36962 | 876 | 82.3 | 24600 | |
| 20131122_01 | 7679 | 41264 | 621 | 101.1 | 31300 | |
| 20131217_01 | 4677 | 27897 | 624 | 150.3 | 42550 | |
| 20131217_03 | 8454 | 46590 | 1304 | 134.9 | 59700 | |
| DG | 20130613_01 | 2503 | 14514 | 318 | 66.0 | 6660 |
| 20131112_01 | 3465 | 16520 | 238 | 95.1 | 9700 | |
| 20131117_02 | 3901 | 19827 | 403 | 130.8 | 17570 | |
| 20131121_03 | 2738 | 12861 | 402 | 106.1 | 8250 |
Basic morphological and membrane properties of hippocampal principal cells as derived for single-cell simulations. The specific membrane capacitance (Cm) was 1 μF/cm2, and the axial resistivity (Ri) 140 Ohm/cm for all cells, Membrane resistivity (Rm) was assumed to be uniform for DGCs and non-uniform for PCs, with 50% lower values at the distal dendrites. The table refers to the proximal Rm value for the non-uniform models. For further detail see Methods.