Table 4.

Exercise performance by tertile of baseline galectin-3 levels

	Low Gal-3 Tertile (N=69)	Mid Gal-3 Tertile (N=70)	High Gal-3 Tertile (N=69)	p-value	p-value†	p-value‡
Peak VO2, mL/kg/min	13.3 (10.8 – 16.2))	11.7 (10.9 – 13.7)	11.1 (9.5 – 13.7)	0.004	0.68	0.24
Respiratory exchange ratio	1.11 (1.03 – 1.18)	1.08 (1.02 – 1.14)	1.09 (1.04 – 1.15)	0.40	0.50	0.48
Peak Systolic BP, mmHg	158 (140 – 174)	157 (133 – 173)	148 (129 – 166)	0.19	0.67	0.61
Rest HR, bpm	70.0 (61.5 – 77.0)	70 (60 – 80)	65 (59 – 75)	0.17	0.46	0.40
Peak HR, bpm	114 (101 – 133)	111 (93 – 128)	97 (86 – 118)	0.003	0.55	0.37
Chronotropic index	0.57 (0.36 – 0.69)	0.53 (0.32 – 0.71)	0.37 (0.25 – 0.61)	0.034	0.74	0.72
VE/VCO2 slope	32.4 (28.2 – 37.1)	31.7 (28.5 – 36.7)	34.1 (28.9 – 37.9)	0.69	0.92	0.99
6-Minute walk distance, meters	310 (251 – 400)	325 (244 – 384)	290 (202 – 349)	0.027	0.46	0.49

Total n with data (201–208);

^†Adjusted for Age, Sex, cystatin-C;

^‡Adjusted for cystatin-C alone.

Abbreviations BP, Blood Pressure; HR, Heart Rate