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. 2015 Feb 28;11(2):73–84. doi: 10.6026/97320630011073

Figure 7.

Figure 7

The favorable binding position of indigocarpan with lowest binding free energy of PDGFRβ (PDB ID: 3MJG) as analyzed by molecular docking study. (a) The three-dimensional diagram displays the interaction of indigocarpan (green stick) with PDGFRβ labeled amino acid residues of THR86 and THR88 which significantly contributed to the binding. (b) The two dimensional diagram shows the interactions of indigocarpan to the amino acid residues in the ATP- binding site. (c & d) denotes the binding mode of Sorafenib with PDGFRβ. Similarly, colors of the residues indicate the forms of interactions as follows: van der Waals forces, green; polarity, magenta; Green arrow represents H-bonding with the amino acid main chain.