Table 1.
Patient demographics and clinical characteristics
| No. of Patients | |
|---|---|
| Sex | |
| Male | 55 |
| Female | 88 |
| Age at diagnosis | |
| Median | 36 years |
| Range | 12–87 years |
| Tumor size | |
| Macroadenoma | 108 |
| Microadenoma | 35 |
| Tumor type | |
| Nonsecreting | 47 |
| Secreting | 96 |
| Prolactin | 55 |
| GH | 11 |
| ACTH | 5 |
| TSH | 1 |
| Prolactin + GH | 5 |
| Mixed other | 19 |
| Treatment | |
| Conservative management | 59 |
| Surgery | 76 |
| Radiation | 29 |
| Surgery plus radiation | 21 |
| Repeat radiation | 5 |
| Extent of primary surgery | |
| Subtotal resection | 11 |
| Radical subtotal resection | 15 |
| Gross total resection | 50 |
| Dose of radiotherapy (cGy) | |
| <3 500 | 8* |
| 3 500–4 499 | 5 |
| 4 500–5 499 | 12 |
| 5 500–6 499 | 4 |
Abbreviations: ACTH, adrenocorticotropic hormone; GH, growth hormone; TSH, thyroid-stimulating hormone.
*2 received radiosurgery 25 Gy in single fraction to tumor margin.