Table 3.
Comparison of survivors meeting versus not meeting Diagnostic and Statistical Manual of Mental Disorders, 4th Edition35 attention deficit/hyperactivity disorder, predominantly inattentive type symptom criteria
| Without ADHD Symptoms | With ADHD Symptoms | Mean Difference (95% CI) | P | |
|---|---|---|---|---|
| M ± SD/ N (%) | M ± SD/ N (%) | |||
| Neurocognitive Outcomesa | N = 37 | N = 11 | ||
| IQ | 98.4 ± 14.93 | 85.6 ± 14.75 | 12.8 (2.4, 23.2) | .02 |
| Working Memory | 98.5 ± 14.23 | 84.8 ± 14.81 | 13.7 (3.8, 23.6) | .008 |
| Processing Speed | 88.4 ± 12.66 | 86.0 ± 11.08 | 2.4 (−6.1, 10.9) | .57 |
| Psychological Outcomesb | N = 47 | N = 18 | ||
| Internalizing Problems | 54.0 ± 10.68 | 58.2 ± 13.27 | −4.2 (−10.5, 2.1) | .19 |
| Externalizing Problems | 46.4 ± 9.47 | 59.8 ± 11.87 | −13.4 (−19.0, −7.8) | <.001 |
| Social Problems | 58.0 ± 7.96 | 64.0 ± 9.6 | −6.0 (−10.7, −1.3) | .01 |
| Demographics | N = 51 | N = 19 | ||
| Male sex | 26 (51.0%) | 13 (68.4%) | −17.4% (11.1, 40.4) | .19 |
| Age | 11.9 ± 3.61 | 10.7 ± 3.56 | 1.2 (−0.7, 3.1) | .24 |
| Medical Variables | N = 51 | N = 19 | ||
| Brain Tumor diagnosis | 34 (66.7%) | 13 (68.4%) | −1.7% (−26.0, 25.0) | .10 |
| Age at Diagnosis (years) | 5.9 ± 3.48 | 4.6 ± 3.48 | 1.3 (−0.6, 3.2) | .18 |
| Years off Treatment | 4.1 ± 2.62 | 4.6 ± 3.47 | −0.5 (−2.0, 1.0) | .53 |
| Cranial Radiation | 25 (49.0%) | 8 (42.1%) | 6.9% (−20.8, 32.3) | .61 |
Abbreviations: ADHD, attention deficit/hyperactivity disorder; DMS-IV, Diagnostic and Statistical Manual of Mental Disorders, 4th Edition.
aStandard Scores: M = 100, SD = 15.
bT-scores: M = 50, SD = 10.
*Participants meeting diagnostic criteria based on questionnaire data. DSM-IV criteria require presence of at least 6 symptoms.