Table 1. (a) The performance comparisons of the co-training model with single and simple combined views of TCM and MM on each syndrome differentiation. (b) The prediction performance of five models on the differentiation of CHB syndromes.
| (a) | ||||
|---|---|---|---|---|
| TCM only | MM only | Simple combination | Co-training | |
| Classifier 1 (Healthy vs. CHB) | ||||
| Acc.(SD) | 0.9445 (0.006) | 0.9509 (0.011) | 0.9546 (0.010) | **0.9778 (0.011) |
| Sen.(SD) | 0.9992 (0.003) | 0.9891 (0.005) | 0.9967 (0.005) | 0.9842 (0.008) |
| Spec.(SD) | 0.1400 (0.138) | 0.5380 (0.232) | 0.4500 (0.178) | **0.824 (0.197) |
| Classifier 2 (NDS vs. DS) | ||||
| Acc.(SD) | 0.9122 (0.016) | 0.9301 (0.008) | 0.9403 (0.011) | **0.9503 (0.025) |
| Sen.(SD) | 0.9884 (0.013) | 0.9984 (0.005) | 1.0000 (0) | 0.9714 (0.025) |
| Spec.(SD) | 0.1600 (0.161) | 0.2875 (0.090) | 0.4150 (0.167) | **0.66 (0.215) |
| Classifier 3 (LGDH vs. LSSD) | ||||
| Acc.(SD) | 0.9385 (0.023) | 0.6489 (0.044) | 0.9329 (0.028) | 0.9141 (0.040) |
| Sen.(SD) | 0.9257 (0.046) | 0.1742 (0.092) | 0.9121 (0.067) | **0.9573 (0.049) |
| Spec.(SD) | 0.9758 (0.027) | 0.9299 (0.045) | 0.9744 (0.023) | 0.8913 (0.057) |
**p < 0.001, *p < 0.01; Random times = 100.
TCM: Traditional Chinese Medicine; MM: Modern Medicine.
Acc: Accuracy; Sen: Sensitivity; Spec: Specificity.
CHB: Chronic Hepatitis B.
LGDH: Liver-Gallbladder Dampness-Heat.
LSSD: Liver-Stagnation Spleen-Deficiency.
NDS: No Distinct Symptom.