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The effects of LATS1 on 17-AAG-treated LAC cells. Lv-LATS1 or Lv-LATS1-siRNA was transfected into 17-AAG (1.0 μmol/l) treated-LAC cells, indicating that cell proliferation (A) and invasion (B and C) of LAC cells were significantly weakened in 17-AAG+Lv-LATS1 group compared to the 17-AAG and CON groups (**P < 0.01), but 17-AAG had no inhibitory effect in Lv-LATS1-siRNA transfected cells compared to non-transfected cells.
