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Sarcolemmal immunolabelling of nNOS in muscle biopsies from patients with sarcoglycanopathies (A-E) and control (F). The reaction was absent in LGMD2E patients with complete SG complex defect (C) and partial in LGMD2E patients with partial SG complex defect (D), indicating that the reduction of nNOS level depends directly on the residual level of SG complex. Scale bar = 50 μm. Original magnification: 200x.
