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Algorithm for ALK screening in lung cancer patients. A. Selection of patients to be included in the screening, based on clinical-pathological and molecular criteria. B. Proposal for different techniques to be used in a large screening program. EGFR, Epidermal Growth Factor Receptor; PPV, positive predictive value; RT-PCR, Reverse transcription polymerase chain reaction; TN, true negative; TP, true positive.
