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Survival and serum BNP concentration across all groups: (a) survival and (b) serum BNP concentration. At the end of follow-up duration, there were 20 survivals in control group, 11 in DOX group, and 16 in DOX + SMI group, respectively. Compared to control group, * P < 0.05; compared to DOX group, # P < 0.05.
