TABLE 1.

Distinctive Characteristics of Hormonal Disorders Associated With Excess Weight Gain

Distinctive Findings	Disorder
Microphallus, neonatal hypoglycemia, giant cell hepatitis	GHD, hypopituitarism
Broad (> 1 cm) hemorrhagic or violaceous striae, muscle wasting, osteoporosis, vertebral fracture	Cushing’s syndrome
Goiter	Hypothyroidism
Lack of satiety, bizarre feeding behavior, temperature instability, rage attacks	Hypothalamic obesity
Galactorrhea	Hyperprolactinemia
Hypoventilation, temperature instability, pain hyposensitivity, neural crest tumors	ROHHAD

GHD = growth hormone deficiency; ROHHAD = rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation.