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Distinctive Characteristics of Monogenic Disorders Associated With Hyperphagia and Infantile Obesity
| Distinctive Findings | Disorder |
|---|---|
| Tall stature | MC4R deficiency |
| Frequent infections | Leptin deficiency, leptin receptor mutations |
| Adrenal crisis | POMC deficiency |
| Diarrhea | Proprotein convertase 1 deficiency |
MC4R = melanocortin 4 receptor; POMC = proopiomelanocortin.
