TABLE 3.
Distinctive Characteristics of Syndromic Disorders Associated with Childhood Obesity
Distinctive Findings | Disorder |
---|---|
Hypotonia, infantile failure to thrive followed by hyperphagia and weight gain, small hands and feet, pain insensitivity, obsessive compulsive behavior | Prader-Willi syndrome |
Visual dysfunction, polydactyly, cardiac/genitourinary/renal anomalies | Bardet-Biedl syndrome |
Visual dysfunction, hearing loss, cardiomyopathy, type 2 diabetes | Alström syndrome |
Short metacarpals, soft tissue calcification | Albright’s hereditary osteodystrophy |
Autism, schizophrenia, cardiac/renal anomalies | Chromosome 16p, 1q deletions |