Table 2.
Prevalence and odds ratios for vascular inflammation and hepatic steatosis across weight and metabolic risk factor based phenotypes.
| Prevalence of Elevated hsCRP | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall | Males only | Females only | |||||||
| n (%) | UOR | AOR | n (%) | UOR | AOR | n (%) | UOR | AOR | |
| Metabolically healthy normal weight (referent) | 223 (12%) | 1 | 1 | 96 (9%) | 1 | 1 | 127 (16%) | 1 | 1 |
| Metabolically unhealthy normal weight | 44 (17%) | 1.51 (1.06–2.14) |
2.00 (1.31–3.06) |
35 (17%) | 2.10 (1.38–3.20) |
1.96 (1.23–3.11) |
9 (18%) | 1.10 (0.52–2.32)* |
1.24 (0.58–2.63)* |
| Metabolically healthy obese | 452 (22%) | 2.11 (1.78–2.52) |
2.45 (1.92–3.12) |
335 (19%) | 2.51 (1.97–3.19) |
2.52 (1.94–3.27) |
117 (40%) | 3.32 (2.45–4.48) |
3.59 (2.63–4.90) |
| Metabolically unhealthy obese | 343 (25%) | 2.46 (2.04–2.96) |
2.89 (2.25–3.73) |
283 (22%) | 3.02 (2.36–3.86) |
2.93 (2.24–3.84) |
60 (56%) | 6.40 (4.18–9.81) |
7.84 (4.95–12.41) |
|
| |||||||||
| Prevalence of Hepatic Steatosis | |||||||||
| Overall | Males Only | Females Only | |||||||
| n (%) | UOR | AOR | n (%) | UOR | AOR | n (%) | UOR | AOR | |
|
| |||||||||
| Metabolically healthy normal weight (referent) | 152 (8%) | 1 | 1 | 137 (13%) | 1 | 1 | 15 (2%) | 1 | 1 |
| Metabolically unhealthy normal weight | 70 (27%) | 4.12 (2.99–5.68) |
3.03 (2.12–4.32) |
62 (30%) | 2.94 (2.08–4.17) |
2.60 (1.82–3.69) |
8 (16%) | 9.30 (3.7–23.15) |
6.67 (2.59–17.18) |
| Metabolically healthy obese | 805 (40%) | 7.49 (6.20–9.05) |
5.80 (4.72–7.13) |
756 (71%) | 5.50 (4.49–6.74) |
5.30 (4.32–6.50) |
49 (17%) | 10.13 (5.58–18.40) |
8.57 (4.67–15.73) |
| Metabolically unhealthy obese | 952 (70%) | 25.76 (21.04–31.54) |
17.64 (14.14–22.01) |
894 (71%) | 17.03 (13.71–21.15) |
15.18 (12.19–19.49) |
58 (56%) | 62.89 (33.08–119.56) |
44.41 (22.81–86.49) |
UOR: unadjusted odds ratio (95% confidence interval).
AOR: adjusted odds ratio (95% confidence interval), adjusted for age, gender, LDL, smoking history, and physical activity.
n (%) represents number and percentage of subjects with outcome of interest (steatosis or elevated hsCRP) among a specific phenotype (MHNW, MUNW, MHO or MUHO).
* P value > 0.05. All other data has associated P < 0.05 unless otherwise noted.