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CARN action during myoblast differentiation: signaling pathway activation. (a) CARN stimuli significantly activate the IGF-1/AKT/p70S6 pathway. (b) CARN supplement did not have any effects on ERKs activation. Representative immunoblots of analyzed proteins are shown. Significance: ∙ P ≤ 0.001 Anova test and * P ≤ 0.05 DM versus CARN at 24, 48, or 72 h.
